Determinants of Treatment Failure in Drug-Resistant  Tuberculosis Patients in Papua Province

Yulpriati Kalua; Hasmi; Sarce Makaba; Arius Togodly; Novita Medyati; Rosmin Mariati Tingginehe

doi:10.55927/fjst.v5i3.34

Authors

Yulpriati Kalua Master of Public Health Study Program, Faculty of Public Health, Cenderawasih University of Jayapura
Hasmi Department of Master of Public Health Program, Faculty of Public Health, Cenderawasih University of Jayapura
Sarce Makaba Department of Master of Public Health Program, Faculty of Public Health, Cenderawasih University of Jayapura
Arius Togodly Department of Master of Public Health Program, Faculty of Public Health, Cenderawasih University of Jayapura
Novita Medyati Department of Master of Public Health Program, Faculty of Public Health, Cenderawasih University of Jayapura
Rosmin Mariati Tingginehe Department of Master of Public Health Program, Faculty of Public Health, Cenderawasih University of Jayapura

DOI:

https://doi.org/10.55927/fjst.v5i3.34

Keywords:

Tuberculosis, Drug-Resistant, Failure, Treatment

Abstract

The purpose of the study was to analyze the determinants of treatment failure in RO tuberculosis patients in Papua Province. Types of analytical observational research with a cross-sectional approach. The population is 471 people, and the sampling is saturated. Data were obtained using secondary data using univariate analysis, bivariate analysis using the Chi-square test, and multivariate analysis using binary logistic regression. The results of the study were found to be 55.4% failed in the treatment of Drug-Resistant TB. Chi-square test results with a p-value of < 0.05 were occupation, OAT side effects, treatment combinations, and adherence to OAT intake. The insignificant variables were age, sex, ethnicity, comorbid DM, comorbid HIV/AIDS, and TB treatment history. Comorbid HIV AIDS is the most dominant factor for treatment failure in RO TB patients

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